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Senior Research Associate, In Vivo Biology


Kyn Therapeutics, an emerging leader in cancer and cancer immuno-therapy, is seeking a talented, diversely experienced and motivated in vivo biologist to join an innovative, scientifically rigorous and fast paced team focused on developing breakthrough cancer therapies. The successful candidate will bring a sense of urgency and commitment to help Kyn Therapeutics reach its potential and deliver novel therapeutics to patients.

‪ Description and accountabilities:

  • In vivo scientist that can design and execute preclinical studies using cancer and immuno-oncology models
  • Experienced working with mouse tumor models, including syngeneic models and performing studies including intravenous, oral, intraperitoneal and sub-cutaneous dosing for pharmacokinetic, pharmacodynamic and efficacy studies
  • Collection of biological samples from mice (tumor, tissues, serum)
  • Develop and conduct assays that support in vivo studies (e.g. qPCR, cytokine analysis)
  • Conduct flow cytometry analysis of tumor immune cells
  • Conduct additional in vitro biology and cell biology experiments as needed
  • Contribute to experimental design of immunology/oncology studies
  • Present research at internal and external meetings


  • BS or MS with in biology/oncology/immunology with two to five years of hands-on in vivo experience
  • Expertise in animal studies including pharmacokinetic and efficacy studies in syngeneic mouse models, working with both biologics and small molecules
  • Skilled in dosing oral, IV and IP
  • Drug discovery experience in immunology and/or oncology
  • Low cytometry experience with immunology background is a plus
  • Willingness to help other members of team

Personal attributes: goal-driven, highly collaborative, open-minded, data-driven, creative, persistent in the face of obstacles and uncertainty, flexible, objective in the evaluation of data and strongly optimistic about overcoming obstacles, excellent oral and written communication skills.

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Kyn Therapeutics
50 Northern Avenue
7th Floor
Boston, MA 02210

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