Harnessing the power of immuno-metabolism.
Reigniting the immune system to attack cancer by disrupting suppressive metabolic pathways
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Reigniting the immune system to attack cancer by disrupting suppressive metabolic pathways

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Kyn Therapeutics is developing cancer therapies focused on metabolic pathways that influence the innate and adaptive immune systems.

Stimulating a strong and broad immune response

By harnessing immuno- metabolic networks, we’re engaging a broad range of immune cell types to improve efficacy and patient response in a wide range of cancer types.

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Common characteristics of an immunosuppressive tumor microenvironment

Increased:

  • Secretion of immunosuppressive molecules
  • Generation of immunosuppressive metabolites
  • Infiltration of regulatory immune cells
  • Incidence of anergic effector T cells

Decreased:

  • Expression of immune-activating molecules
  • Penetration of proinflammatory helper and effector immune cells
  • Tumor antigen presentation

Overcoming local tumor defenses

At Kyn, we are focused on enhancing immunity and breaking down the broad range of cancer defenses so immune cells can reach and eradicate the tumor.

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Our pipeline

The Kyn Therapeutics pipeline addresses three distinct immuno-metabolic targets. Each of these programs target key metabolites in highly characterized pathways that drive immunosuppression in numerous cancer types.

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Kyn Therapeutics
1030 Massachusetts Avenue
Suite 400
Cambridge, MA 02138

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1-857-273-8343

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info@kyntherapeutics.com

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